Ned K |
| Catalog No.GC50308 |
Ned K es un antagonista del fosfato de dinucleótido de adenina del ácido nicotínico (NAADP).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2250019-90-8
Sample solution is provided at 25 µL, 10mM.
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NAADP inhibitor. Prevents Ca2+ oscillations in rat cardiomyocytes in vitro during simulated ischemia and reperfusion, but exhibits no significant effect on Ca2+ sparks. Significantly reduces infarct size in rat cardiac ischemia/reperfusion model in vivo.
Davidson et al (2015) Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore. Cardiovasc.Res. 108 357 PMID:26395965
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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