PD-159020 |
| Catalog No.GC34031 |
PD-159020 es un antagonista no selectivo de ETA/ETB, con IC50 de 30 y 50 nM para hETA y hETB, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 177904-00-6
Sample solution is provided at 25 µL, 10mM.
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PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively.
PD-159020 demonstrates excellent inhibition of arachidonic acid release, AAR-B, with an IC50 of 0.23 μM.
[1]. Amy Mbunker, et al. 1,3-diaryl-2-carboxyindoles as potent non-peptide endothelin antagonists. Bioorganic & Medicinal Chemistry Letters. Volume 6, Issue 9, 7 May 1996, Pages 1061-1066
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