Adaptive Immunity
Products for Adaptive Immunity
- Cat.No. Nombre del producto Información
-
GC45194
α-(difluoromethyl)-DL-Arginine
Bacteria synthesize the cellular growth factor putrescine through a number of pathways.
- GC50708 (±)-ML 209 An RORγt antagonist
- GC41703 (E)-C-HDMAPP (ammonium salt) Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes.
- GC49028 (S)-3-Thienylglycine A thienyl-containing amino acid
- GC49768 1,1’-Ethylidene-bis-(L-tryptophan) A potential impurity found in commercial preparations of L-tryptophan
- GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.
- GC18376 1-Palmitoleoyl glycerol 1-Palmitoleoyl glycerol is a bioactive monoacylglycerol.
- GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC La 1-palmitoil-2-hidroxi-sn-glicero-3-PC es una abundante LPC gonadal (lisofosfatidilcolina).
- GC45693 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC46400 10(11)-Cl-BBQ Mixture A mixture that acts as an AhR agonist
- GC52343 113-O12B An ionizable cationic lipidoid
- GC46415 12-Bromododecanoic Acid A halogenated form of lauric acid
- GC49759 13C17-Mycophenolic Acid An internal standard for the quantification of mycophenolic acid
- GC18778 16,16-dimethyl Prostaglandin A1 16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1.
- GC42112 2-Acetyl-5-tetrahydroxybutyl Imidazole Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.
- GC46553 2-Nonylquinolin-4(1H)-one A quinolone alkaloid with diverse biological activities
- GC52446 2-Nonylquinolin-4(1H)-one-d4 An internal standard for the quantification of 2-nonylquinolin-4(1H)-one
- GC46549 2F-Peracetyl-Fucose 2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) actÚa como un potente inhibidor de fucosiltransferasa (FUT).
- GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide
- GC42259 3-Deaza-2'-deoxyadenosine 3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM.
- GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin
- GC49206 7α-hydroxy Dehydroepiandrosterone An active metabolite of dehydroepiandrosterone
- GC46740 7β,27-dihydroxy Cholesterol An oxysterol and agonist of RORγ and RORγt
- GC46733 7,12-Dimethylbenz[a]anthracene El 7,12-dimetilbenz[a]antraceno tiene actividad cancerÍgena como hidrocarburo aromÁtico policÍclico (HAP). El 7,12-dimetilbenz[a]antraceno se usa para inducir la formaciÓn de tumores en varios modelos de roedores.
- GC42623 8-Bromoguanosine 8-Bromoguanosine is a brominated derivative of guanosine.
- GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).
- GC42668 ABC34 ABC34 is an inactive control probe for JJH260, the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC42685 Ac-ANW-AMC Ac-ANW-AMC es un sustrato fluorogénico para el inmunoproteasoma.
- GC18443 Acetyl-6-formylpterin Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.
- GC45681 AKP-11 An S1P1 receptor agonist
- GC45790 Artesunate-d4 El artesunato-d4 es artesunato marcado con deuterio. El artesunato es un inhibidor tanto de STAT-3 como de la proteÍna exportada 1 (EXP1).
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells).
- GC42891 azido-FTY720 Azido-FTY720 es un anÁlogo fotoactivable de FTY720.
- GC49044 Benastatin C A bacterial metabolite with diverse biological activities
- GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37
- GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI (clorhidrato) (Ro 32-0432) es un inhibidor de PKC potente, selectivo y activo por vía oral con IC50 de 9 nM, 28 nM, 31 nM, 37 nM y 108 nM para PKCα, PKCβI, PKCβII, PKCγ y PKCε , respectivamente.
- GA20972 Boc-D-Leu-OSu An amino acid-containing building block
- GC52101 Brazilein La brazileÍna es un importante componente inmunosupresor aislado de Caesalpinia sappan L.
- GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid.
- GC43032 C16 Globotriaosylceramide (d18:1/16:0) C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide.
- GC43049 C18 Globotriaosylceramide (d18:1/18:0) C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide.
- GC40709 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
-
GC43084
C4 Ceramide (d18:1/4:0)
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC40688 C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).
- GC40690 C6 L-threo Ceramide (d18:1/6:0) C6 L-threo Ceramide (d18:1/6:0) es un esfingolÍpido bioactivo y un anÁlogo permeable a las células de las ceramidas naturales.
- GC47040 Carebastine-d5 An internal standard for the quantification of carebastine
- GC43181 CAY10597 The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2.
- GC40757 CAY10734 An S1P1 receptor agonist
- GC48427 CAY10774 A PD-1/PD-L1 interaction inhibitor
- GC49664 CB-1158 An arginase inhibitor
- GC49584 CD74 Monoclonal Antibody (Clone PIN1) For immunochemical analysis of CD74
- GC18392 Cellocidin Cellocidin is an antibiotic originally isolated from S.
- GC43239 Chk2 Inhibitor El inhibidor de Chk2 (compuesto 1) es un inhibidor potente y selectivo de la quinasa de punto de control 2 (Chk2), con IC50 de 13,5 nM y 220,4 nM para Chk2 y Chk1, respectivamente. El inhibidor de Chk2 puede provocar un fuerte efecto de radioprotecciÓn mediado por Chk2 dependiente de ataxia telangiectasia mutada (ATM).
- GC52153 CIN-16645 CIN-16645 es un lÍpido catiÓnico Útil en el suministro de agentes biolÓgicamente activos a células y tejidos (extraÍdo de la patente WO2015095340 A1).
- GC47109 Clotrimazole-d5 An internal standard for the quantification of clotrimazole
- GC43288 Cochlioquinone A Cochlioquinone A, a bioactive compound isolated from D.
- GC43307 Concanamycin B Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM).
-
GC18572
Concanavalin A
La concanamicina A pertenece a las concanamicinas, una familia de antibióticos macrólidos aislados de Streptomyces diastatochromogenes que son inhibidores altamente activos y selectivos de la vacuolar proton-ATPasa (v-[H+] ATPasa).
- GC49021 CXCR3 Antagonist 6c A CXCR3 antagonist
- GC43340 Cyclic di-IMP (sodium salt) Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP.
- GC43350 Cyclosporin B La ciclosporina B es un grupo de oligopéptidos cÍclicos no polares con actividad inmunosupresora.
- GC49526 Cytidine-d2 An internal standard for the quantification of cytidine
- GC49153 Didemnin B La didemnina B es un depsipéptido cíclico producido por tunicados marinos que se une específicamente a la conformación unida a GTP de EEF1A.
- GC40629 Dimethoxycurcumin La dimetoxicurcumina es un derivado de la curcumina que tiene actividades antiinflamatorias y antioxidantes.
- GC43467 Dimethyldioctadecylammonium (bromide) Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid.
- GC48352 Diprovocim-1 An agonist of TLR1/TLR2
-
GC47257
Dodecanoyl D-Sucrose
Un surfactante no iónico
- GC40082 Drimentine B Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.
- GC47278 Ebastine-d5 An internal standard for the quantification of ebastine
- GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil
- GC43659 Feglymycin Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities.
- GC18325 Ferrichrome (iron-free) Ferrichrome is a hydroxamate siderophore produced by various fungi, including U.
- GC46148 Filgotinib-d4 Filgotinib-d4 (GLPG0634-d4) es el Filgotinib marcado con deuterio. Filgotinib (GLPG0634) es un inhibidor selectivo de JAK1 con IC50 de 10 nM, 28 nM, 810 nM y 116 nM para JAK1, JAK2, JAK3 y TYK2, respectivamente.
- GC47351 Fingolimod-d4 An internal standard for the quantification of fingolimod
- GC47352 FK-506-13C-d2 An internal standard for the quantification of FK-506
- GC52014 Forphenicinol An immunomodulator and a derivative of forphenicine
-
GC40887
FTY720 (R)-Phosphate
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
- GC47387 G6PDi-1 G6PDi-1 es un inhibidor reversible y no competitivo de glucosa-6-fosfato deshidrogenasa (G6PD) con una IC50 de 0,07 μM.
- GC18469 Galactosylcerebrosides (bovine) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with hydroxy and non-hydroxy fatty acids.
- GC43721 Galactosylcerebrosides (hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43722 Galactosylcerebrosides (non-hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43730 Ganglioside GM1 Asialo Mixture Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase.
- GC47392 Ganglioside GM1 Mixture (ovine) (ammonium salt) A mixture of ganglioside GM1
- GC47398 Genistein-d4 La genisteÍna-d4 (NPI 031L-d4) es la genisteÍna marcada con deuterio. La genisteÍna, una isoflavona de soja, es un inhibidor de mÚltiples tirosina quinasas (por ejemplo, EGFR) que actÚa como agente quimioterapéutico contra diferentes tipos de cÁncer, principalmente alterando la apoptosis, el ciclo celular y la angiogénesis e inhibiendo la metÁstasis.
- GC47403 Gliovirin La gliovirina es un antibiÓtico activo contra Pythium ultimum.
- GC49798 Glyphosine A plant growth regulator
- GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.
-
GC43807
HDMAPP (ammonium salt)
HDMAPP is a metabolite of the microbial dioxyxylulose-phosphate pathway, which is analogous to the isopentenyl pyrophosphate pathway in mammals.
- GC47434 Homodestcardin La homodestcardina, un ciclodepsipéptido basado en destruxina, es un inmunosupresor.
- GC43879 Hydroxy Ebastine Hydroxy Ebastine is an ebastine metabolite.
- GC49282 Hydroxy Lenalidomide A metabolite of lenalidomide
- GC48548 iBET-BD2 A BD2 bromodomain inhibitor
- GC47456 Indole-3-pyruvic Acid El Ácido indol-3-pirÚvico, un cetoanÁlogo del triptÓfano, es un agonista de AHR activo por vÍa oral.
- GC40901 Isogarcinol Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia.
- GC52321 ISP-I-28 An immunosuppressant
- GC43928 JJH260 JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC47533 L-778,123 A dual inhibitor of FTase and GGTase I
- GC47552 Leflunomide-d4 La leflunomida-d4 (HWA486-d4) es la leflunomida marcada con deuterio. La leflunomida es un inhibidor de la sÍntesis de pirimidina que inhibe la dihidroorotato deshidrogenasa (DHODH) y actÚa como un fÁrmaco antirreumÁtico modificador de la enfermedad.
- GC47553 Lenalidomide-d5 An internal standard for the quantification of lenalidomide