GLPBio

TAE648

Catalog No.: GC84973Purity:>99.50%Synonyms: TL13-87
COASDSData Sheet
TAE648 is a target protein ligand of PROTAC SK-3-91 ( Ligand for Target Protein for PROTAC ).

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TAE648
Cas No.: 2769753-10-6
10mM (in 1mL DMSO)In Stock
$195.00
1
5mgIn Stock
$182.00
1
10mgIn Stock
$292.00
1
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Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Descripción (Description)

TAE648 is a target protein ligand of PROTAC SK-3-91 ( Ligand for Target Protein for PROTAC ). TAE648 can be used for synthesis PROTAC [1]. TAE648 decreases monolayer-cultured SKOV3ip1 cell viability [2].

References:
[1]. Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183(6):1714-1731.e10.
[2]. Cha HJ, et al. Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells. Int J Oncol. 2017 Apr;50(4):1279-1288.
[3]. Hellwig S, et al. Small-molecule inhibitors of the c-Fes protein-tyrosine kinase[J]. Chemistry & biology, 2012, 19(4): 529-540.

Documentos del producto (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

N.º CAS
2769753-10-6
Sinónimos
TL13-87
Fórmula molecular
C23H27ClN6O2S
Peso molecular
487.02
Solubilidad
DMSO: 100 mg/mL (205.33 mM; Need ultrasonic)
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

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