GLPBio

TAE648

Catalog No.: GC84973Purity:>99.50%Synonyms: TL13-87
COASDSData Sheet
TAE648 is a target protein ligand of PROTAC SK-3-91 ( Ligand for Target Protein for PROTAC ).

Products are for research use only. Not for human use. We do not sell to patients.

TAE648
Cas No.: 2769753-10-6
10mM (in 1mL DMSO)In Stock
$195.00
1
5mgIn Stock
$182.00
1
10mgIn Stock
$292.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

TAE648 is a target protein ligand of PROTAC SK-3-91 ( Ligand for Target Protein for PROTAC ). TAE648 can be used for synthesis PROTAC [1]. TAE648 decreases monolayer-cultured SKOV3ip1 cell viability [2].

References:
[1]. Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183(6):1714-1731.e10.
[2]. Cha HJ, et al. Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells. Int J Oncol. 2017 Apr;50(4):1279-1288.
[3]. Hellwig S, et al. Small-molecule inhibitors of the c-Fes protein-tyrosine kinase[J]. Chemistry & biology, 2012, 19(4): 529-540.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2769753-10-6
Synonyms
TL13-87
Molecular Formula
C23H27ClN6O2S
Molecular Weight
487.02
Solubility
DMSO: 100 mg/mL (205.33 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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