ATP synthase inhibitor 1 |
| رقم الكتالوجGC35421 |
مثبط سينثيز ATP 1 هو مثبط قوي للوحدة الفرعية c لمركب سينسيز F1 / FO-ATP ، ويثبط فتح مسام انتقال نفاذية الميتوكوندريا (mPTP) ، ولا يؤثر على مستويات ATP
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Cas No.: 1023043-30-2
Sample solution is provided at 25 µL, 10mM.
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ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1]. F1/FO-ATP synthase[1]
ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex[1].
[1]. Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61(16):7131-7143.
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