JTV-519 free base (Synonyms: K201 free base) |
| カタログ番号GC36371 |
JTV-519 遊離塩基 (K201 遊離塩基) は、筋小胞体 Ca2+- 刺激 ATPase (SERCA) の Ca2依存性ブロッカーであり、横紋筋のリアノジン受容体の部分アゴニストです。
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Cas No.: 145903-06-6
Sample solution is provided at 25 µL, 10mM.
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JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].
[1]. Darcy YL, et al. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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