JTV-519 free base (Synonyms: K201 free base) |
| Katalog-Nr.GC36371 |
Die freie Base JTV-519 (freie Base K201) ist ein Ca2+--abhÄngiger Blocker der Ca2+--stimulierten ATPase (SERCA) des sarkoplasmatischen Retikulums und ein partieller Agonist der Ryanodinrezeptoren im quergestreiften Muskel.
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Cas No.: 145903-06-6
Sample solution is provided at 25 µL, 10mM.
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JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].
[1]. Darcy YL, et al. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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