الصفحة الرئيسية>>Signaling Pathways>> GPCR/G protein>> Prostaglandin Receptor>>Travoprost

Travoprost (Synonyms: AL-6221, Flu-Ipr, 16mtrifluoromethylphenoxy tetranor PGF2α isopropyl ester, Travoprost)

رقم الكتالوجGC37822

Travoprost (Fluprostenol isopropyl ester) ، وهو عقار أولي إستر إيزوبروبيل ، هو ناهض مستقبلات FP انتقائي كامل للبروستاجلاندين

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Travoprost التركيب الكيميائي

Cas No.: 157283-68-6

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
82٫00
متوفر
1mg
37٫00
متوفر
5mg
74٫00
متوفر
10mg
111٫00
متوفر
25mg
167٫00
متوفر
50mg
240٫00
متوفر
100mg
361٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description of Travoprost

Travoprost is used to treat glaucoma and ocular hypertension.Target: OthersTravoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes. From Wikipedia.

[1]. http://en.wikipedia.org/wiki/Travoprost

Chemical Properties of Travoprost

Cas No. 157283-68-6 SDF
المرادفات AL-6221, Flu-Ipr, 16mtrifluoromethylphenoxy tetranor PGF2α isopropyl ester, Travoprost
Canonical SMILES O=C(OC(C)C)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C[C@@H]1O
Formula C26H35F3O6 M.Wt 500.55
الذوبان Ethanol: 60 mg/mL (119.87 mM); DMSO: ≥ 41.67 mg/mL (83.25 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Travoprost

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.9978 mL 9.989 mL 19.978 mL
5 mM 0.3996 mL 1.9978 mL 3.9956 mL
10 mM 0.1998 mL 0.9989 mL 1.9978 mL
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In vivo Formulation Calculator (Clear solution) of Travoprost

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Travoprost

Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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