H3B-120 |
| رقم الكتالوجGC39648 |
H3B-120 هو مثبط انتقائي للغاية وتنافسي وفوسفات مركب 1 (CPS1) مع IC من 1.5 ميكرومتر وكي 1.4 ميكرومترH3B-120 له نشاط مضاد للسرطان
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Cas No.: 2194903-42-7
Sample solution is provided at 25 µL, 10mM.
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H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity[1].
[1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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