H3B-120 |
Catalog No.GC39648 |
H3B-120은 IC50이 1.5μM이고 Ki가 1.4μM인 고도로 선택적이고 경쟁적인 알로스테릭 카바모일 인산 합성효소 1(CPS1) 억제제입니다. H3B-120은 항암 활성이 있습니다.
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Cas No.: 2194903-42-7
Sample solution is provided at 25 µL, 10mM.
H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity[1].
[1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.
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