H3B-120 |
カタログ番号GC39648 |
H3B-120 は、1.5 μM の IC50 と 1.4 μM の Ki を持つ、高度に選択的で競合的でアロステリックなカルバモイルリン酸シンテターゼ 1 (CPS1) 阻害剤です。 H3B-120 には抗がん作用があります。
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Cas No.: 2194903-42-7
Sample solution is provided at 25 µL, 10mM.
H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity[1].
[1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.
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