PUMA BH3 |
| رقم الكتالوجGC34389 |
PUMA BH3 عبارة عن مُعدِّل p53 مُنظم لببتيد مجال موت الخلايا المبرمج (PUMA) BH3 ، يعمل كمنشط مباشر لـ Bak ، مع Kd 26 نانومتر
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Sample solution is provided at 25 µL, 10mM.
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PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak[1].
[1]. Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.
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