PUMA BH3 |
| Katalog-Nr.GC34389 |
PUMA BH3 ist ein p53-hochreguliertes Modulator-of-Apoptose (PUMA)-BH3-DomÄnenpeptid, das als direkter Aktivator von Bak wirkt, mit einem Kd von 26 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak[1].
[1]. Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.
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