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Startseite >> Signaling Pathways >> Immunology/Inflammation >> Autoimmunity

Autoimmunity

Produkte für  Autoimmunity

  1. Bestell-Nr. Artikelname Informationen
  2. GC52253 α-Enolase (1-19)-biotin Peptide A biotinylated α-enolase peptide α-Enolase (1-19)-biotin Peptide Chemical Structure
  3. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanozyten-stimulierendes Hormon) TFA, ein endogenes Neuropeptid, ist ein endogener Melanocortinrezeptor 4 (MC4R)-Agonist mit entzÜndungshemmenden und antipyretischen AktivitÄten. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  4. GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  5. GC45263 (+)-D-threo-PDMP (hydrochloride) (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. (+)-D-threo-PDMP (hydrochloride) Chemical Structure
  6. GC52185 (R,S)-Anatabine-d4 (R,S)-Anatabine-d4 Chemical Structure
  7. GC49759 13C17-Mycophenolic Acid An internal standard for the quantification of mycophenolic acid 13C17-Mycophenolic Acid Chemical Structure
  8. GC49912 13C20,15N10-Cyclic di-GMP (sodium salt) An internal standard for the quantification of cyclic di-GMP 13C20,15N10-Cyclic di-GMP (sodium salt) Chemical Structure
  9. GC41950 16α-hydroxy Estrone 16α-Hydroxy Estrone (16αOHE) ist ein Hauptmetabolit von Estradiol. 16α-hydroxy Estrone Chemical Structure
  10. GC42080 2'2'-cGAMP (sodium salt) 2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. 2'2'-cGAMP (sodium salt) Chemical Structure
  11. GC40960 20α-dihydro Prednisolone 20α-dihydro Prednisolone is a metabolite of prednisolone. 20α-dihydro Prednisolone Chemical Structure
  12. GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen 4'-hydroxy Flurbiprofen Chemical Structure
  13. GC49127 4-oxo Cyclophosphamide An inactive metabolite of cyclophosphamide 4-oxo Cyclophosphamide Chemical Structure
  14. GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam 5'-hydroxy Meloxicam Chemical Structure
  15. GC48381 5'-pApA (sodium salt) A linearized form of cyclic di-AMP 5'-pApA (sodium salt) Chemical Structure
  16. GC48375 5'-pGpG (sodium salt) A linearized form of cyclic di-GMP 5'-pGpG (sodium salt) Chemical Structure
  17. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  18. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  19. GC45772 6(5H)-Phenanthridinone An inhibitor of PARP1 and 2 6(5H)-Phenanthridinone Chemical Structure
  20. GC49235 6-Methylmercaptopurine A metabolite of 6-mercaptopurine 6-Methylmercaptopurine Chemical Structure
  21. GC49488 6-Methylmercaptopurine-d3 An internal standard for the quantification of 6-MMP 6-Methylmercaptopurine-d3 Chemical Structure
  22. GC49051 7-hydroxy Methotrexate 7-Hydroxy-Methotrexat ist ein Hauptmetabolit von Methotrexat 7-hydroxy Methotrexate Chemical Structure
  23. GC42608 7-hydroxy Methotrexate (sodium salt)

    7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.

     7-hydroxy Methotrexate (sodium salt) Chemical Structure
  24. GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). 9-Deazaguanine Chemical Structure
  25. GC49238 93-O17S A cationic lipidoid 93-O17S Chemical Structure
  26. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester Chemical Structure
  27. GC42692 Aceclofenac methyl ester A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester Chemical Structure
  28. GC40645 Actarit Actarit, ein oral aktiver antirheumatischer Wirkstoff, hat das Potenzial, durch Kollagen Typ II verursachte Arthritis zu behandeln. Actarit Chemical Structure
  29. GC45681 AKP-11 An S1P1 receptor agonist AKP-11 Chemical Structure
  30. GC46867 Apremilast-d5 Apremilast D5 (CC-10004 D5) ist ein Deuterium mit der Bezeichnung Apremilast. Apremilast-d5 Chemical Structure
  31. GC45790 Artesunate-d4 Artesunat-d4 ist Deuterium mit der Bezeichnung Artesunat. Artesunat ist ein Inhibitor sowohl von STAT-3 als auch von exportiertem Protein 1 (EXP1). Artesunate-d4 Chemical Structure
  32. GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities Aurintricarboxylic Acid (ammonium salt) Chemical Structure
  33. GC49646 Aurothioglucose (hydrate) A TrxR inhibitor Aurothioglucose (hydrate) Chemical Structure
  34. GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells). AUY954 Chemical Structure
  35. GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Avenanthramide-C methyl ester Chemical Structure
  36. GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) ist eine starke und lang wirkende entzÜndungshemmende und fiebersenkende Verbindung. Benoxaprofen Chemical Structure
  37. GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) Chemical Structure
  38. GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM). BMS 345541 (trifluoroacetate salt) Chemical Structure
  39. GC46946 BPC 157 (acetate) A pentadecapeptide with diverse biological activities BPC 157 (acetate) Chemical Structure
  40. GC46983 C-170 C-170 (C-170) ist ein potenter und kovalenter STING-Inhibitor. C-170 Chemical Structure
  41. GC46984 C-171 C-171 ist ein Inhibitor des Stimulators von Interferon-Genen (STING). C-171 Chemical Structure
  42. GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid. C12 Galactosylceramide (d18:1/12:0) Chemical Structure
  43. GC43076 C24 Phytosphingosine (t18:0/24:0) C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) Chemical Structure
  44. GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) Chemical Structure
  45. GC47020 Calcium D-Glucarate (hydrate) The calcium salt form of D-glucaric acid Calcium D-Glucarate (hydrate) Chemical Structure
  46. GC49147 Carboxyphosphamide An inactive metabolite of cyclophosphamide Carboxyphosphamide Chemical Structure
  47. GC43176 CAY10575 CAY10575 (Verbindung 8) ist ein IKK2-Inhibitor mit einem IC50 von 0,075 μM. CAY10575 Chemical Structure
  48. GC47054 CAY10748 A STING agonist CAY10748 Chemical Structure
  49. GC45885 Chloroquine-d5 (phosphate) An internal standard for the quantification of chloroquine Chloroquine-d5 (phosphate) Chemical Structure
  50. GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide Chemical Structure
  51. GC52363 Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide

    A biotinylated and citrullinated histone H3 peptide

     Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide Chemical Structure
  52. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide Chemical Structure
  53. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide Chemical Structure
  54. GC49680 Clobetasone Propionate A corticosteroid Clobetasone Propionate Chemical Structure
  55. GC18572 Concanavalin A

    Concanamycin A gehört zu den Concanamycinen, einer Familie von Makrolid-Antibiotika, die aus Streptomyces diastatochromogenes isoliert wurden und hochaktive und selektive Hemmstoffe der Vakuolären Protonen-ATPase (v-[H+]ATPase) sind.

     Concanavalin A Chemical Structure
  56. GC45413 Cridanimod (sodium salt)   Cridanimod (sodium salt) Chemical Structure
  57. GC45614 Cryogenine An alkaloid with anti-inflammatory activity Cryogenine Chemical Structure
  58. GC47128 CU-32 A cGAS inhibitor CU-32 Chemical Structure
  59. GC47129 CU-76 A cGAS inhibitor CU-76 Chemical Structure
  60. GC43339 Cyclic di-AMP (sodium salt) Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria but not by mammals. Cyclic di-AMP (sodium salt) Chemical Structure
  61. GC19526 Cyclic di-GMP (sodium salt) Zyklisches di-GMP (Natriumsalz) ist ein STING-Agonist und ein bakterieller Second Messenger, der verschiedene Aspekte des Bakterienwachstums und -verhaltens koordiniert, einschließlich MotilitÄt, Virulenz, Biofilmbildung und Fortschreiten des Zellzyklus. Zyklisches di-GMP (Natriumsalz) hat eine Anti-KrebszellproliferationsaktivitÄt und induziert auch eine erhÖhte CD4-Rezeptorexpression und einen Zellzyklusarrest. Zyklisches di-GMP (Natriumsalz) kann in der Krebsforschung eingesetzt werden. Cyclic di-GMP (sodium salt) Chemical Structure
  62. GC43340 Cyclic di-IMP (sodium salt) Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP. Cyclic di-IMP (sodium salt) Chemical Structure
  63. GC48397 Cyclic di-UMP (sodium salt) A pyrimidine-containing CDN Cyclic di-UMP (sodium salt) Chemical Structure
  64. GC47148 Cyclophosphamide-d4 Cyclophosphamid-d4 ist das mit Deuterium markierte Cyclophosphamid. Cyclophosphamid ist ein synthetisches Alkylierungsmittel, das chemisch mit Stickstofflost mit antineoplastischer AktivitÄt, einem Immunsuppressivum, verwandt ist. Cyclophosphamide-d4 Chemical Structure
  65. GC47193 Desethyl Hydroxychloroquine-d4 An internal standard for the quantification of desethyl hydroxychloroquine Desethyl Hydroxychloroquine-d4 Chemical Structure
  66. GC43444 Diclofenac Acyl-β-D-Glucuronide Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat. Diclofenac Acyl-β-D-Glucuronide Chemical Structure
  67. GC47212 Diclofenac amide A prodrug form of diclofenac Diclofenac amide Chemical Structure
  68. GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  69. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4 Chemical Structure
  70. GC40867 Diflorasone Diacetate Diflorasondiacetat ist eine entzÜndungshemmende Steroidverbindung, die als lokales oder topisches Mittel verwendet wird. Diflorasone Diacetate Chemical Structure
  71. GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP (hydrochloride) Chemical Structure
  72. GC52334 ENPP1 Inhibitor 4e An ENPP1 inhibitor ENPP1 Inhibitor 4e Chemical Structure
  73. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  74. GC47323 Etofenamate-d4 An internal standard for the quantification of etofenamate Etofenamate-d4 Chemical Structure
  75. GC40565 Feprazone Feprazone (DA2370; Prenazone), ein Analogon von Phenylbutazon, ist ein nichtsteroidales entzÜndungshemmendes Mittel mit analgetischer und fiebersenkender Wirkung. Feprazone Chemical Structure
  76. GC46148 Filgotinib-d4 Filgotinib-d4 (GLPG0634-d4) ist das mit Deuterium gekennzeichnete Filgotinib. Filgotinib (GLPG0634) ist ein selektiver JAK1-Inhibitor mit IC50-Werten von 10 nM, 28 nM, 810 nM und 116 nM fÜr JAK1, JAK2, JAK3 bzw. TYK2. Filgotinib-d4 Chemical Structure
  77. GC47366 Flurbiprofen-d3 An internal standard for the quantification of flurbiprofen Flurbiprofen-d3 Chemical Structure
  78. GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase Forphenicine Chemical Structure
  79. GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid Ganglioside GM4 (chicken egg) (ammonium salt) Chemical Structure
  80. GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. Halofuginone (hydrochloride) Chemical Structure
  81. GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline Homocitrulline-d3 Chemical Structure
  82. GC47445 Hydroxychloroquine-d4 (sulfate) An internal standard for the quantification of hydroxychloroquine Hydroxychloroquine-d4 (sulfate) Chemical Structure
  83. GC43894 IKK2 Inhibitor VI

    Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.

     IKK2 Inhibitor VI Chemical Structure
  84. GC40901 Isogarcinol Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. Isogarcinol Chemical Structure
  85. GC52291 KAS 08 A STING activator KAS 08 Chemical Structure
  86. GC52394 LC10 A lipidoid derivative of lithocholic acid LC10 Chemical Structure
  87. GC47552 Leflunomide-d4 Leflunomid-d4 (HWA486-d4) ist das mit Deuterium bezeichnete Leflunomid. Leflunomid ist ein Pyrimidinsynthesehemmer, der die Dihydroorotatdehydrogenase (DHODH) hemmt und als krankheitsmodifizierendes Antirheumatikum wirkt. Leflunomide-d4 Chemical Structure
  88. GC44078 LL-37 amide (trifluoroacetate salt) LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. LL-37 amide (trifluoroacetate salt) Chemical Structure
  89. GC41452 Luteoloside Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. Luteoloside Chemical Structure
  90. GC49916 Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) A bradykinin B1 receptor antagonist Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) Chemical Structure
  91. GC47649 Methotrexate (hydrate) A folic acid and aminopterin derivative Methotrexate (hydrate) Chemical Structure
  92. GC47650 Methotrexate-d3 An internal standard for the quantification of methotrexate Methotrexate-d3 Chemical Structure
  93. GC45998 Mitoxantrone-d8 Mitoxantron-d8 (Mitozantron-d8) ist das mit Deuterium bezeichnete Mitoxantron. Mitoxantron ist ein Topoisomerase-II-Inhibitor und hemmt auch die AktivitÄt der Proteinkinase C (PKC) mit einer IC50 von 8,5 μM. Mitoxantrone-d8 Chemical Structure
  94. GC52419 MOG (35-55) (mouse, rat) (trifluoroacetate salt) An MOG antigen peptide MOG (35-55) (mouse, rat) (trifluoroacetate salt) Chemical Structure
  95. GC47712 Mycophenolate Mofetil-d4 Mycophenolate Mofetil-d4 ist das mit Deuterium bezeichnete Mycophenolate Mofetil. Mycophenolatmofetil (RS 61443) ist das Morpholinoethylester-Prodrug von MycophenolsÄure. Mycophenolatmofetil hemmt die De-novo-Purinsynthese Über die Hemmung der Inosinmonophosphatdehydrogenase (IMPDH). Mycophenolatmofetil zeigt selektive antiproliferative Wirkungen auf Lymphozyten, die sowohl T- als auch B-Zellen betreffen und die Bildung von AntikÖrpern verhindern. Mycophenolate Mofetil-d4 Chemical Structure
  96. GC52385 Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) An MBP (85-99) antagonist Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) Chemical Structure
  97. GC44257 Myelin Basic Protein (87-99) (human, bovine, rat) (trifluoroacetate salt) Myelin basic protein (MPB) (87-99) is an encephalitogenic peptide. Myelin Basic Protein (87-99) (human, bovine, rat) (trifluoroacetate salt) Chemical Structure
  98. GC40298 N-acetyl-5-Aminosalicylic Acid N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine. N-acetyl-5-Aminosalicylic Acid Chemical Structure
  99. GC44388 NF-κB Control NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. NF-κB Control Chemical Structure
  100. GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB NF-κB Inhibitor (trifluoroacetate salt) Chemical Structure
  101. GC18895 NIBR0213 NIBR-0213 ist ein potenter und selektiver S1P1-Antagonist mit Wirksamkeit bei experimenteller autoimmuner Enzephalomyelitis. NIBR0213 Chemical Structure

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