SW155246 |
| رقم الكتالوجGC18642 |
SW155246 هو مثبط انتقائي لنقل ميثيل الحمض النووي (DNMT1) مع IC50s من 1.2 و 38 ميكرومتر لـ hDNMT1 و mDNMT3A ، على التوالييمكن استخدام SW155246 في أبحاث السرطان والأمراض الأخرى
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 420092-79-1
Sample solution is provided at 25 µL, 10mM.
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SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.
Review for SW155246
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
Review for SW155246
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