SW155246 |
| Katalog-Nr.GC18642 |
SW155246 ist ein DNA-Methyltransferase (DNMT1)-selektiver Inhibitor mit IC50-Werten von 1,2 und 38 μM fÜr hDNMT1 bzw. mDNMT3A. SW155246 kann fÜr die Erforschung von Krebs und anderen Krankheiten verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 420092-79-1
Sample solution is provided at 25 µL, 10mM.
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SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.
Review for SW155246
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
Review for SW155246
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