SW155246 |
| Catalog No.GC18642 |
SW155246 est un inhibiteur sélectif de l'ADN méthyltransférase (DNMT1) avec des IC50 de 1,2 et 38 μM pour hDNMT1 et mDNMT3A, respectivement. SW155246 peut être utilisé pour la recherche sur le cancer et d'autres maladies.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 420092-79-1
Sample solution is provided at 25 µL, 10mM.
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SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.
Review for SW155246
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
Review for SW155246
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