TA 01 |
| رقم الكتالوجGC13825 |
TA 01 هو مثبط قوي لـ CK1 و p38 MAPK ، مع IC50s من 6.4 نانومتر ، 6.8 نانومتر ، 6.7 نانومتر لـ CK1ε ، CK1δ و p38 MAPK ، على التوالي.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1784751-18-3
Sample solution is provided at 25 µL, 10mM.
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TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 (5 μM) is not cytotoxic, completely inhibits cardiogenesis, but induces cardiogenesis at lower concentration[1].
Reference:
[1]. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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