Target Protein-binding moiety 13 (Synonyms: PROTAC FKBP12-binding moiety 1) |
| رقم الكتالوجGC33200 |
جزء ربط البروتين المستهدف 13 (جزء ربط PROTAC FKBP12 1) عبارة عن رابط تركيبي لـ FKBP (SLF). يمكن استخدام جزء ربط البروتين المستهدف 13 (جزء ربط PROTAC FKBP12 1) في تخليق PROTACs.
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Cas No.: 1092369-24-8
Sample solution is provided at 25 µL, 10mM.
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Target Protein-binding moiety 13 is a synthetic ligand for FKBP (SLF), which is used in the synthesis of PROTACs.
Target Protein-binding moiety 13 (SLF building block 2) is a synthetic ligand for FKBP (SLF). SLF is composed of only one half of FK506 and it is known to have a significantly weaker affinity for FKBP12.
[1]. Dunyak BM, et al. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of TwoIntracellular Proteins. ACS Chem Biol. 2015 Nov 20;10(11):2441-7.
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