الصفحة الرئيسية>>Signaling Pathways>> Cell Cycle/Checkpoint>> Microtubule/Tubulin>>Tubulin inhibitor 6

Tubulin inhibitor 6 (Synonyms: Improved Heterocyclic Activator of PP2A 1, Tubulin Inhibitor 6)

رقم الكتالوجGC39558

مثبط توبولين 6 (المركب 14 ب) هو مثبط للتوبولين ومثبط قوي لخطوط الخلايا السرطانية المتعددةمثبط التوبولين 6 يثبط بلمرة التوبولين باستخدام IC50 من 0.87 ميكرومترمثبط توبولين 6 يمنع نمو خلية K562 مع IC50 من 840 نانومتر

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Tubulin inhibitor 6 التركيب الكيميائي

Cas No.: 105925-39-1

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
102٫00
متوفر
5mg
93٫00
متوفر
10mg
139٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].

[1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

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