Tubulin inhibitor 6 (Synonyms: Improved Heterocyclic Activator of PP2A 1, Tubulin Inhibitor 6) |
Catalog No.GC39558 |
튜불린 억제제 6(화합물 14b)은 튜불린 억제제이자 여러 암 세포주의 강력한 억제제입니다. 튜불린 억제제 6은 0.87μM의 IC50으로 튜불린 중합을 억제합니다. 튜불린 억제제 6은 840nM의 IC50으로 K562 세포 성장을 억제합니다.
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Cas No.: 105925-39-1
Sample solution is provided at 25 µL, 10mM.
Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].
[1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.
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