Tubulin inhibitor 6 (Synonyms: Improved Heterocyclic Activator of PP2A 1, Tubulin Inhibitor 6) |
| Katalog-Nr.GC39558 |
Tubulin-Inhibitor 6 (Verbindung 14b) ist ein Tubulin-Inhibitor und ein potenter Inhibitor mehrerer Krebszelllinien. Tubulin-Inhibitor 6 hemmt die Tubulin-Polymerisation mit einer IC50 von 0,87 μM. Tubulin-Inhibitor 6 hemmt das Wachstum von K562-Zellen mit einer IC50 von 840 nM.
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Cas No.: 105925-39-1
Sample solution is provided at 25 µL, 10mM.
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Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].
[1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.
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