VH 032, phenol |
| Catalog No.GC50607 |
VH 032, 페놀은 VH032 기반 VHL 리간드입니다. VH 032, 페놀은 링커에 의해 단백질에 대한 리간드에 연결되어 PROTAC를 형성할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2244684-42-0
Sample solution is provided at 25 µL, 10mM.
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Maniaci et al (2017) Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat.Comm. 8 830 PMID:29018234
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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