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VH 032, phenol

カタログ番号GC50607

VH 032、フェノールは VH032 ベースの VHL リガンドです。 VH 032、フェノールは、リンカーによってタンパク質のリガンドに接続され、PROTAC を形成します。

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VH 032, phenol 化学構造

Cas No.: 2244684-42-0

サイズ 価格 在庫数 個数
50 mg
$657.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Maniaci et al (2017) Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat.Comm. 8 830 PMID:29018234

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