GLPBio

Membrane Transporter/Ion Channel

Research Areas

Products Related to Membrane Transporter/Ion Channel(2450)

  • GC79498 structure
    GC79498Calciseptine TFA
    Purity: >97.50%

    Calciseptine TFA, a polypeptide found in black mamba venom, is a selcetive Cav1.2 L-type calcium channel inhibitor with an IC 50 of 92 nM.

  • GC79499 structure
    GC79499RyR1-IN-1
    CAS: 2837939-81-6
    Purity: >98.00%

    RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC 50 of 12 nM.

  • GC79500 structure
    GC79500OV329 hydrochloride
    CAS: 2093928-29-9
    Purity: >99.50%

    OV329 hydrochloride is a potent GABA aminotransferase inactivator.

  • GC79501 structure
    GC79501GABA-palmitamide
    CAS: 58725-44-3
    Purity: >98.50%

    GABA-palmitamide is a GABA-responsive compound.

  • GC79502 structure
    GC79502mNLS-CPP-WSTF TFA
    Purity: >96.00%

    mNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF.

  • GC79503 structure
    GC79503mNLS-CPP-scramble TFA
    Purity: >98.00%

    mNLS-CPP-scramble (TFA) is the trifluoroacetate salt of mNLS-CPP-scramble.

  • GC79504 structure
    GC79504(R)-Verapamil
    CAS: 38321-02-7
    Purity: >98.50%

    (R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil.

  • GC79505 structure
    GC79505RPI-GLYT2-82
    Purity: >99.00%

    RPI-GLYT2-82 is a reversible, blood-brain barrier-permeable allosteric inhibitor of GlyT2 with an IC 50 value of 554 nM.

  • GC79506 structure
    GC79506Blixeprodil hydrochloride
    CAS: 3048183-44-1
    Purity: >97.00%

    Blixeprodil hydrochloride (GM-1020 hydrochloride) is an orally active, blood-brain barrier-penetrant NMDA receptor inhibitor with a K i of 3.25 µM in rat cortical tissues.

  • GC79507 structure
    GC79507PSB-12054
    CAS: 1407632-07-8
    Purity: >98.50%

    PSB-12054 is a P2X4 receptor antagonist with IC 50 values of 0.19 μM, 2.10 μM and 1.77 μM against human, rat and mouse receptors, respectively, and exhibits selectivity over other human P2X receptor subtypes.

  • GC79508 structure
    GC79508GluN2B-NMDAR Allosteric modulator 1
    CAS: 2419700-58-4
    Purity: >99.50%

    GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator.

  • GC79509 structure
    GC79509UCM-A86
    CAS: 1210899-51-6
    Purity: >98.50%

    UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively.

  • GC79510 structure
    GC79510AMPA receptor modulator-10
    CAS: 620940-01-4
    Purity: >98.50%

    AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor ( AMPAR ) positive allosteric modulator.

  • GC79511 structure
    GC79511JNJ-78911118
    CAS: 3106013-91-3
    Purity: >99.00%

    JNJ-78911118 is a potent, brain-penetrant, selective GluN2A antagonist ( IC 50 = 44 nM).

  • GC79512 structure
    GC79512Sepimostat trifluoroacetate
    Purity: >99.50%

    Sepimostat (FUT-187) trifluoroacetate exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit.

  • GC79513 structure
    GC79513Lemairamin
    CAS: 29946-61-0
    Purity: >99.50%

    Lemairamin (Wgx-50) is a hydroxylamine compound.

  • GC79514 structure
    GC79514(S)-6-Methylnicotine
    CAS: 13270-56-9
    Purity: >98.00%

    (S)-6-Methylnicotine is a nicotinic acetylcholine receptor ( nAChR ) agonist that exhibits agonistic activity on isolated guinea pig ileum.

  • GC79515 structure
    GC79515Hydrohydrastinine
    CAS: 494-55-3
    Purity: >99.50%

    Hydrohydrastinine is a selective α4β2 nicotinic acetylcholine receptor antagonist with an IC 50 of 2.6 μM and a K i of 17 μM.

  • GC79516 structure
    GC79516nAChR antagonist 3
    CAS: 3114746-65-2
    Purity: >98.00%

    nAChR antagonist 3 is a selective α7 nAChR antagonist with an IC 50 of 0.86 μM.

  • GC79517 structure
    GC79517RGH-857
    CAS: 2408754-53-8
    Purity: >98.00%

    RGH-857 is an orally active, selective, potent nicotinic α7 positive allosteric modulator.

  • GC79518 structure
    GC79518Spinosyn L
    CAS: 149092-01-3
    Purity: >98.00%

    Spinosyn L is a selective nicotinic acetylcholine receptors ( nAChR ) agonist.

  • GC79519 structure
    GC79519SKF-96365
    CAS: 162849-90-3
    Purity: >99.50%

    SKF-96365 is a TRPC channel antagonist and store-operated calcium entry ( SOCE ) inhibitor.

  • GC79520 structure
    GC79520Nav1.2-IN-2
    CAS: 7469-49-0
    Purity: >99.50%

    Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC 50 of 0.18 μM.

  • GC79521 structure
    GC79521CAD204520 dihydrochloride
    CAS: 2682205-21-4
    Purity: >99.00%

    CAD204520 dihydrochloride, a SERCA inhibitor ( IC 50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).