Membrane Transporter/Ion Channel
Research Areas
- AMPAR(55)
- Aquaporins(3)
- Piezo Channels(6)
- ATPase(79)
- Calcium Channel(356)
- Cannabinoid Transporters(6)
- CFTR(51)
- Chloride Channels(12)
- GABA Receptor(202)
- Glucose Transporters(17)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(30)
- ICB(1)
- MCT2(2)
- Monoamine transporter(16)
- Monocarboxylate Transporters(14)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(16)
- NKCC(9)
- NMDA Receptor(77)
- Nucleoside Transporters(6)
- Pannexin-1(2)
- P2X purinergic receptor(70)
- P-gp(10)
- Proton Pump(59)
- Potassium Channel(335)
- Sodium Channel(226)
- TRP Channel(190)
- TRPV1(10)
- URAT1(14)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(11)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(31)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(10)
- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(31)
- P-glycoprotein(60)
- iGluR(182)
- nAChR(121)
- VDAC(3)
- GlyR(1)
- Ferroportin(4)
- Urea Transporter(1)
- Na+/H+ Exchanger (NHE)(2)
- NTPDase(4)
- EAAT(5)
- ASCT(3)
- Apical Sodium-Dependent Bile Acid Transporter(1)
- Sec61(2)
- ATP-binding cassette (ABC) transporters(5)
- SLC39 (Zinc Transporter)(2)
- Sodium Phosphate Cotransporter(1)
Products Related to Membrane Transporter/Ion Channel(2432)
- GC79493F3288-0031CAS: 926493-93-8Purity: >98.00%
F3288-0031 is a brain-penetrant norepinephrine transporter ( NET ) allosteric inhibitor with inhibitory rates of 73.5% at 20 μM.
- GC79494ATPase-IN-7CAS: 816450-73-4Purity: >99.50%
ATPase-IN-7 (Example 1) is a H + /K + -ATPase inhibitor.
- GC79498Calciseptine TFAPurity: >97.50%
Calciseptine TFA, a polypeptide found in black mamba venom, is a selcetive Cav1.2 L-type calcium channel inhibitor with an IC 50 of 92 nM.
- GC79500OV329 hydrochlorideCAS: 2093928-29-9Purity: >99.50%
OV329 hydrochloride is a potent GABA aminotransferase inactivator.
- GC79501GABA-palmitamideCAS: 58725-44-3Purity: >98.50%
GABA-palmitamide is a GABA-responsive compound.
- GC79502mNLS-CPP-WSTF TFAPurity: >96.00%
mNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF.
- GC79503mNLS-CPP-scramble TFAPurity: >98.00%
mNLS-CPP-scramble (TFA) is the trifluoroacetate salt of mNLS-CPP-scramble.
- GC79504(R)-VerapamilCAS: 38321-02-7Purity: >98.50%
(R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil.
- GC79505RPI-GLYT2-82Purity: >99.00%
RPI-GLYT2-82 is a reversible, blood-brain barrier-permeable allosteric inhibitor of GlyT2 with an IC 50 value of 554 nM.
- GC79506Blixeprodil hydrochlorideCAS: 3048183-44-1Purity: >97.00%
Blixeprodil hydrochloride (GM-1020 hydrochloride) is an orally active, blood-brain barrier-penetrant NMDA receptor inhibitor with a K i of 3.25 µM in rat cortical tissues.
- GC79508GluN2B-NMDAR Allosteric modulator 1CAS: 2419700-58-4Purity: >99.50%
GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator.
- GC79510AMPA receptor modulator-10CAS: 620940-01-4Purity: >98.50%
AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor ( AMPAR ) positive allosteric modulator.
- GC79511JNJ-78911118CAS: 3106013-91-3Purity: >99.00%
JNJ-78911118 is a potent, brain-penetrant, selective GluN2A antagonist ( IC 50 = 44 nM).
- GC79512Sepimostat trifluoroacetatePurity: >99.50%
Sepimostat (FUT-187) trifluoroacetate exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit.
- GC79514(S)-6-MethylnicotineCAS: 13270-56-9Purity: >98.00%
(S)-6-Methylnicotine is a nicotinic acetylcholine receptor ( nAChR ) agonist that exhibits agonistic activity on isolated guinea pig ileum.
- GC79515HydrohydrastinineCAS: 494-55-3Purity: >99.50%
Hydrohydrastinine is a selective α4β2 nicotinic acetylcholine receptor antagonist with an IC 50 of 2.6 μM and a K i of 17 μM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79492 | ML077 | 1135304-61-8 | >98.00% | |
ML007 is a selective antagonist targeting the neuron-specific potassium-chloride co-transporter 2 ( KCC2 ) with an IC 50 for KCC2 is 537 nM, while its inhibitory activity on KCC1 is extremely weak ( IC 50 > 50 μM). | ||||
| GC79493 | F3288-0031 | 926493-93-8 | >98.00% | |
F3288-0031 is a brain-penetrant norepinephrine transporter ( NET ) allosteric inhibitor with inhibitory rates of 73.5% at 20 μM. | ||||
| GC79494 | ATPase-IN-7 | 816450-73-4 | >99.50% | |
ATPase-IN-7 (Example 1) is a H + /K + -ATPase inhibitor. | ||||
| GC79495 | slCeMM1 | 949973-22-2 | >98.00% | |
slCeMM1 is a selective SLC16A3 ( MCT4 ) inhibitor. | ||||
| GC79496 | NS-6740 | 753500-02-6 | >99.50% | |
NS-6740 is a silent agonist of α7 nicotinic acetylcholine receptor ( α7 nAChR ) with an IC 50 of 3 nM. | ||||
| GC79497 | Pincainide | 83471-41-4 | >98.00% | |
Pincainide is a calcium channel inhibitor. | ||||
| GC79498 | Calciseptine TFA | - | >97.50% | |
Calciseptine TFA, a polypeptide found in black mamba venom, is a selcetive Cav1.2 L-type calcium channel inhibitor with an IC 50 of 92 nM. | ||||
| GC79499 | RyR1-IN-1 | 2837939-81-6 | >98.00% | |
RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC 50 of 12 nM. | ||||
| GC79500 | OV329 hydrochloride | 2093928-29-9 | >99.50% | |
OV329 hydrochloride is a potent GABA aminotransferase inactivator. | ||||
| GC79501 | GABA-palmitamide | 58725-44-3 | >98.50% | |
GABA-palmitamide is a GABA-responsive compound. | ||||
| GC79502 | mNLS-CPP-WSTF TFA | - | >96.00% | |
mNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF. | ||||
| GC79503 | mNLS-CPP-scramble TFA | - | >98.00% | |
mNLS-CPP-scramble (TFA) is the trifluoroacetate salt of mNLS-CPP-scramble. | ||||
| GC79504 | (R)-Verapamil | 38321-02-7 | >98.50% | |
(R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil. | ||||
| GC79505 | RPI-GLYT2-82 | - | >99.00% | |
RPI-GLYT2-82 is a reversible, blood-brain barrier-permeable allosteric inhibitor of GlyT2 with an IC 50 value of 554 nM. | ||||
| GC79506 | Blixeprodil hydrochloride | 3048183-44-1 | >97.00% | |
Blixeprodil hydrochloride (GM-1020 hydrochloride) is an orally active, blood-brain barrier-penetrant NMDA receptor inhibitor with a K i of 3.25 µM in rat cortical tissues. | ||||
| GC79507 | PSB-12054 | 1407632-07-8 | >98.50% | |
PSB-12054 is a P2X4 receptor antagonist with IC 50 values of 0.19 μM, 2.10 μM and 1.77 μM against human, rat and mouse receptors, respectively, and exhibits selectivity over other human P2X receptor subtypes. | ||||
| GC79508 | GluN2B-NMDAR Allosteric modulator 1 | 2419700-58-4 | >99.50% | |
GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator. | ||||
| GC79509 | UCM-A86 | 1210899-51-6 | >98.50% | |
UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively. | ||||
| GC79510 | AMPA receptor modulator-10 | 620940-01-4 | >98.50% | |
AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor ( AMPAR ) positive allosteric modulator. | ||||
| GC79511 | JNJ-78911118 | 3106013-91-3 | >99.00% | |
JNJ-78911118 is a potent, brain-penetrant, selective GluN2A antagonist ( IC 50 = 44 nM). | ||||
| GC79512 | Sepimostat trifluoroacetate | - | >99.50% | |
Sepimostat (FUT-187) trifluoroacetate exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. | ||||
| GC79513 | Lemairamin | 29946-61-0 | >99.50% | |
Lemairamin (Wgx-50) is a hydroxylamine compound. | ||||
| GC79514 | (S)-6-Methylnicotine | 13270-56-9 | >98.00% | |
(S)-6-Methylnicotine is a nicotinic acetylcholine receptor ( nAChR ) agonist that exhibits agonistic activity on isolated guinea pig ileum. | ||||
| GC79515 | Hydrohydrastinine | 494-55-3 | >99.50% | |
Hydrohydrastinine is a selective α4β2 nicotinic acetylcholine receptor antagonist with an IC 50 of 2.6 μM and a K i of 17 μM. | ||||