1α-Hydroxy-3-epi-vitamin D3 |
| Catalog No.GC62761 |
1α ; - L'hydroxy-3-épi-vitamine D3, un métabolite naturel de la 1alpha,25-dihydroxyvitamine D3, est un puissant suppresseur de la sécrétion de l'hormone parathyroÏdienne (PTH).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58028-00-5
Sample solution is provided at 25 µL, 10mM.
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1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion[1].
1 alpha, 25(OH)2D3 is an important negative regulator of parathyroid hormone (PTH) gene transcription[1]. In ROS 17/2.8 cells, 1α-OHD3 (10 μM) not only metabolized into 1αOH-3-epi-D3 and 1α,25(OH)2D3 but also 1α,25(OH)2-3-epi-D3[2].
[1]. A J Brown, et al. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. J Cell Biochem. 1999 Apr 1;73(1):106-13.
[2]. Alex J Brown, et al. Isolation and identification of 1alpha-hydroxy-3-epi-vitamin D3, a potent suppressor of parathyroid hormone secretion. J Cell Biochem
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