10(11)-Cl-BBQ Mixture |
| Catalog No.GC46400 |
A mixture that acts as an AhR agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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10(11)-Cl-BBQ mixture contains the 10-Cl-BBQ and 11-Cl-BBQ congeners of Cl-BBQ and acts as an aryl hydrocarbon receptor (AhR) agonist.1 It induces transcription of the AhR target cytochrome P450 (CYP) isoform Cyp1a1 in mouse liver when administered intraperitoneally at a dose of 10 mg/kg. This product is a mixture of 10-Cl-BBQ and 11-Cl-BBQ.
1.Ehrlich, A.K., Pennington, J.M., Bisson, W.H., et al.TCDD, FICZ, and other high affinity AhR ligands dose-dependently determine the fate of CD4+ T cell differentiationToxicol. Sci.161(2)310-320(2018)
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