A 85380 dihydrochloride |
| Catalog No.GC50088 |
High affinity and selective α4β2 nAChR agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 174740-86-4
Sample solution is provided at 25 µL, 10mM.
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High affinity and selective α4β2 nACh receptor agonist (Ki values are 0.05, 148 and 314 nM for α4β2, α7 and α1β1δγ receptors respectively). Stimulates cation efflux in K177 cells expressing α4β2.
Abreo et al (1996) Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors. J.Med.Chem. 39 817 PMID:8632405 |Sullivan et al (1996) A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand. Neuropharmacology 35 725 PMID:8887981
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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