Acemetacin |
Catalog No.GC10454 |
L'acémétacine (TVX 1322) est un anti-inflammatoire non stéroÏdien et un ester d'acide glycolique de l'indométacine qui est un inhibiteur de la cyclooxygénase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 53164-05-9
Sample solution is provided at 25 µL, 10mM.
Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin. From Wikipedia.
References:
[1]. Tavares IA, et al. Non-steroidal anti-inflammatory drugs that cause relatively little gastric damage. J Gastroenterol Hepatol. 1998 Nov;13(S3):S190-S192.
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