Afoxolaner |
| Catalog No.GC39248 |
Afoxolaner est un insecticide/acaricide isoxazoline actif par voie orale contre Ixodes scapularis chez le chien.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1093861-60-9
Sample solution is provided at 25 µL, 10mM.
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Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod[1][2].
[1]. Mitchell EB, et al. Efficacy of afoxolaner against Ixodes scapularis ticks in dogs.Vet Parasitol. 2014 Apr 2;201(3-4):223-5. [2]. Beugnet F, et al. Afoxolaner against fleas: immediate efficacy and resultant mortality after short exposure on dogs.Parasite. 2014;21:42.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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