Aumitin |
| Catalog No.GC62853 |
L'aumitine est un inhibiteur de l'autophagie À base de diaminopyrimidine qui inhibe la respiration mitochondriale en ciblant le complexe I.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 946293-78-3
Sample solution is provided at 25 µL, 10mM.
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Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].
[1]. Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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