Aumitin |
| Katalog-Nr.GC62853 |
Aumitin ist ein Diaminopyrimidin-basierter Autophagie-Hemmer, der die mitochondriale Atmung hemmt, indem er auf Komplex I abzielt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 946293-78-3
Sample solution is provided at 25 µL, 10mM.
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Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].
[1]. Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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