Caerulomycin A (Cerulomycin) |
| Catalog No.GC30960 |
Caerulomycin A (Cerulomycin) (Cerulomycin; Caerulomycin), un composé antifongique, induit la génération de lymphocytes T, améliore la signalisation de la protéine TGF-β -Smad3 en supprimant la signalisation STAT1 induite par l'interféron-γ.
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Cas No.: 21802-37-9
Sample solution is provided at 25 µL, 10mM.
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Caerulomycin A (Cerulomycin) is a bipyridyl compound, induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases[1].
[1]. Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.
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