MPro Inhibitor 11b |
| Catalog No.GC47708 |
L'inhibiteur MPro 11b est un inhibiteur covalent SARS-CoV-2 3CLpro, avec une IC50 de 40 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2413716-71-7
Sample solution is provided at 25 µL, 10mM.
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MPro inhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50 = 0.04 µM in a TR-FRET assay).1 It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50 = 0.72 µM). MPro inhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 µM.
1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main proteaseScience368(6497)1331-1335(2020)
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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