CIM 0216 |
Catalog No.GC50188 |
CIM 0216, un ligand TRPM3 synthétique, agit comme un agoniste puissant et sélectif de TRPM3.
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Cas No.: 1031496-06-6
Sample solution is provided at 25 µL, 10mM.
Selective TRPM3 agonist. Exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. Stimulates insulin release from pancreatic islet cells in vitro. Evokes nocifensive behavior in mice.
Held et al (2015) Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. Proc.Natl.Acad.Sci.U.S.A. 112 E1363 PMID:25733887
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