DprE1-IN2 |
| Catalog No.GC18263 |
DprE1-IN2 (composé 18) est un puissant inhibiteur de DprE1 avec une IC50 de 28 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1615713-87-5
Sample solution is provided at 25 µL, 10mM.
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DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect[1].
DprE1-IN-2 (compound 18; oral; 100 mg/kg) has t1/2 of 0.9 hours and Cmax of 70 μM in BALB/c Mice[1].
References:
[1]. Shirude PS et al. Lead optimization of 1,4-azaindoles as antimycobacterial agents. J Med Chem. 2014 Jul 10;57(13):5728-37.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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