Edicotinib (Synonyms: JNJ-40346527; JNJ-527) |
| Catalog No.GC19418 |
L'edicotinib (JNJ-40346527) est un inhibiteur puissant, sélectif, pénétrant dans le cerveau et actif par voie orale du récepteur du facteur 1 stimulant les colonies (CSF-1R)avec une CI50 de 3,2nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1142363-52-7
Sample solution is provided at 25 µL, 10mM.
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Edicotinib is a selective and orally available colony-stimulating factor-1 (CSF-1) receptor inhibitor, and has entered phase IIA clinical trial to study rheumatoid arthritis (RA) despite disease.
[1]. Genovese MC, et al. Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy. J Rheumatol. 2015 Oct;42(10):1752-60.
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
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