Dolastatin 15 (Synonyms: NSC 617668) |
| Catalog No.GA21397 |
La dolastatine 15 (DLS 15), un depsipeptide dérivé de Dolabella auricularia, est un puissant agent antimitotique structurellement apparenté À l'agent antitubuline Dolastatine 10. La dolastatine 15 induit l'arrêt du cycle cellulaire et l'apoptose dans les cellules de myélome multiple. La dolastatine 15 peut être utilisée comme cytotoxine ADC.
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Cas No.: 123884-00-4
Sample solution is provided at 25 µL, 10mM.
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Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic
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