ASP6432 |
| Catalog No.GC35409 |
ASP6432 est un antagoniste puissant et sélectif du récepteur de l'acide lysophosphatidique de type 1 (LPA1) avec des IC50 de 11 nM et 30 nM pour le LPA1 humain et le LPA1 de rat, respectivement .
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Cas No.: 1282549-08-9
Sample solution is provided at 25 µL, 10mM.
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ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively[1]. IC50: 11 nM (human LPA1), 30 nM (rat LPA1)[1]
ASP6432 inhibits the LPA-induced proliferation of human prostate stromal cells[1].
[1]. Sakamoto K, et al. Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation. J Pharmacol Exp Ther. 2018 Aug;366(2):390-396.
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