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Autogramin-2

Catalog No.GC35434

L'autogramine-2 inhibe puissamment l'autophagie induite par la famine (IC50 = 0, 27 μM) ou l'inhibition de mTORC1 (Rapamycine; IC50 = 0, 14 μM).

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Autogramin-2 Chemical Structure

Cas No.: 2375541-45-8

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Autogramin-2 potently inhibits autophagy induced by either starvation (IC50=0.27 μM) or mTORC1 inhibition (Rapamycin; IC50=0.14 μM)[1].

[1]. Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.

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Average Rating: 5 ★★★★★ (Based on Reviews and 18 reference(s) in Google Scholar.)

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