Barnidipine |
| Catalog No.GC35469 |
La barndipine (Mepirodipine) est un antagoniste du calcium de type L (CaA) avec une affinité élevée pour les sites de liaison [3H] initrendipine (Ki = 0,21 nmol/l), a une action sélective contre les récepteurs CaA .
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Cas No.: 104713-75-9
Sample solution is provided at 25 µL, 10mM.
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Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors[1].Barnidipine (Mepirodipine) is an antihypertensive drug and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action[2]. Ki: 0.21 nmol/l ([3H] initrendipine)[1]
[1]. van Zwieten PA, et al. Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist. Blood Press Suppl. 1998;1:5-8 [2]. Malhotra HS, et al. Barnidipine. Drugs. 2001;61(7):989-96; discussion 997-8.
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