Mps1-IN-3 |
| Catalog No.GC36651 |
Mps1-IN-3 est un inhibiteur puissant et sélectif de la kinase MPS1, avec une IC50 de 50 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1609584-72-6
Sample solution is provided at 25 µL, 10mM.
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Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM. Mps1|50 nM (IC50)
Mps1-IN-3 is a potent MPS1 kinase inhibitor, with an IC50 of 50 nM. Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells with an IC50 of appr 5 µM. Mps1-IN-3 (2 μM) can completely abrogates checkpoint[1].
Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models, with prolonged survival and no toxicity[1].
[1]. Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105(17):1322-31.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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