Mps1-IN-3 |
| カタログ番号GC36651 |
Mps1-IN-3 は強力で選択的な MPS1 キナーゼ阻害剤であり、IC50 は 50 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1609584-72-6
Sample solution is provided at 25 µL, 10mM.
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Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM. Mps1|50 nM (IC50)
Mps1-IN-3 is a potent MPS1 kinase inhibitor, with an IC50 of 50 nM. Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells with an IC50 of appr 5 µM. Mps1-IN-3 (2 μM) can completely abrogates checkpoint[1].
Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models, with prolonged survival and no toxicity[1].
[1]. Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105(17):1322-31.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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