PTD-p65-P1 Peptide |
| Catalog No.GC37036 |
Le peptide PTD-p65-P1 est un inhibiteur puissant et sélectif du facteur de transcription nucléaire NF-κB et dérive de la sous-unité p65 des résidus d'acides aminés NF-κB 271-282, qui inhibe sélectivement l'activation de NF-κB induite par diverses stimulations inflammatoires, régulent l'expression génique médiée par NF-κB et régulent À la hausse l'apoptose .
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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PTD-p65-P1 Peptide is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1]. NF-kappaB[1]
[1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.
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