PTD-p65-P1 Peptide |
| Catalog No.GC37036 |
PTD-p65-P1 펩타이드는 강력한 선택적 핵 전사 인자 NF-κB 억제제이며 다양한 염증 자극에 의해 유도되는 NF-κB 활성화를 선택적으로 억제하는 NF-κB 아미노산 잔기 271-282의 p65 서브유닛에서 파생됩니다. NF-κB 매개 유전자 발현을 조절하고 세포 사멸을 상향 조절합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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PTD-p65-P1 Peptide is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1]. NF-kappaB[1]
[1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.
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