SHR1653 |
| Catalog No.GC37635 |
SHR1653 est un antagoniste des récepteurs de l'ocytocine (OTR) très puissant, sélectif et pénétrant dans le cerveau, avec une IC50 de 15 nM pour hOTR.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2231770-73-1
Sample solution is provided at 25 µL, 10mM.
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SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR[1]. IC50: 15 nM (hOTR)[1].
[1]. Li X, et al. Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration. ACS Med Chem Lett. 2019 May 29;10(6):996-1001.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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