Vicagrel |
| Catalog No.GC37901 |
Vicagrel est un agent antiplaquettaire puissant, sÛr et actif par voie orale, qui agit en inhibant de manière irréversible le récepteur P2Y12.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1314081-53-2
Sample solution is provided at 25 µL, 10mM.
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Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis, the substrate of carboxylesterase 2 (CES2)[1]. Vicagrel demonstrates a favorable safety profile and excellent anti-platelet activity, which could be an anti-platelet drug and for the unmet medical needs of cardiovascular diseases[2].
[1]. Liu C, et al. Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing. Eur J Pharm Sci. 2019 Jan 15;127:151-160. [2]. Li X, et al. Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers. Front Pharmacol. 2018 Jun 20;9:643.
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