3-Oxocholic Acid (Synonyms: 3-Dehydrocholic Acid) |
Catalog No.GC45339 |
L'acide 3-oxocholique est un métabolite de l'acide oxo-biliaire et également un produit de dégradation majeur de l'acide cholique par C.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2304-89-4
Sample solution is provided at 25 µL, 10mM.
3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid in C. perfringens, a bacteria found in the intestines of mammals and in the environment.[1],[2] 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.[3]
References
[1]. Wahlstr•m, A., Sayin, S.I., Marschall, H.-I., et al. Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism. Cell Metab. 24(1), 41-50 (2016).
[2]. Macdonald, I.A., Forrest, T.P., Costain, G.A., et al. Identification of 7α-, 12α-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringens. J. Steroid Biochem. 9(4), 353-358 (1978).
[3]. Yan, K., Chen, W., Zhu, H., et al. The changes of serum metabolites in diabetic GK rats after ileal transposition surgery. Obes. Surg. 29(3), 882-890 (2019).
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